 |
Lung
Study
Volunteers,
age 8 or older, with a CF genotype of DF508/DF508 or two known CFTR genotype alleles (see list below)
may be eligible. If
you decide to participate, you will be one of approximately 1500
subjects from around the country participating in this study. We will
collect a blood sample from you, for DNA testing, and review some
clinical information about your disease course. We are particularly
interested in those volunteers greater then 32 years old. Privacy
will be protected.
CFTR Genotype Alleles
DF508
G542X
G551D R553X
W1282X
N1303K
3905insT 1078delT
621+1G>T
DI507
R560T S549N
3659delC
G480C 1717-1G>A
Any stop mutation (CFTR Genotype ending in “X”)
Liver
Study
Volunteers with CF,
regardless of genotype and age, who have “severe” liver
disease with portal hypertension (big spleen, i.e.
“splenomegaly” and/or esophageal varices) may be eligible
to participate. This would include any person who has been
evaluated for a liver transplant, or has already received a liver
transplant. If you participate, you will be one of
approximately 500 individuals worldwide contributing to this
study. We will collect a blood sample from you, for DNA testing,
and review some clinical information about your disease course.
Privacy will be protected.
|
 |
